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Ana Lilia Perea Rojas (2023, [Tesis de maestría])
La Reserva de la Biósfera de Bahía de Los Ángeles, Canales de Ballenas y de Salsipuedes (RB-BLACS) es un área natural protegida que provee de distintos servicios ambientales a los pobladores de la comunidad de Bahía de Los Ángeles. Tiene una gran importancia ecológica por la diversidad de especies que habitan en ella y para las especies migratorias que la utilizan, algunas de las cuales se encuentran enlistadas dentro de la NOM-059-SEMARNAT-2001. Con objeto de estimar el efecto de la pesca sobre el ecosistema se construyó un modelo de balance de masas empleando Ecopath con Ecosim. Mediante una revisión documental, se definieron 32 grupos funcionales (GF) y se construyó una matriz de dietas. El modelo se parametrizó con los valores de biomasa (B), relación producción/biomasa (P/B) y se obtuvieron los valores de eficiencia ecotrófica (EE) y relación producción/consumo (P/Q). El rendimiento total del sistema (TST) fue de 13,689 t/km2/año. El nivel trófico de la captura de 3.48 y la producción neta del sistema de 4,641 t/km2/año. La matriz de impactos tróficos mixtos muestra que los grupos que sufren mayor impacto negativo por los Tiburones son los Odontocetos, Misticetos y Tortugas. Se simularon los cambios en la biomasa relativa de los GF bajo escenarios de incremento y decremento del esfuerzo pesquero (5 y 10%) y no pesca, en un lapso de 10 años. Se encontró que los cambios en el esfuerzo pesquero de Elasmobranquios y los Peces de escama son los que mayor efecto tienen sobre otros GF. Resalta que suspender la pesca tendría poco efecto, tanto positivo como negativo (2-3%) sobre la biomasa relativa de los GF, excepto Tiburones y rayas, que incrementarían 245 y 124%, respectivamente. Este modelo podría utilizarse para la toma de decisiones en el manejo y conservación del ecosistema.
The Biosphere Reserve of Bahía de Los Ángeles, Canales de Ballenas y de Salsipuedes (RB-BLACS) is a natural protected area that provides different environmental services to the residents of the community of Bahía de Los Ángeles. It has great ecological importance due to the diversity of species that inhabit it and the migratory species that use it, some of which are listed within NOM-059- SEMARNAT-2001. To estimate the effect of fishing on the ecosystem, a mass balance model was built using Ecopath with Ecosim. Through a documentary review, 32 functional groups (GF) were defined, and a diet matrix was constructed. The model was parameterized with the values of biomass (B), production/biomass ratio (P/B) and the values of ecotrophic efficiency (EE) and production/consumption ratio (P/Q) were obtained. The total system throughput (TST) was 13,689 t/km2/year. The trophic level of the capture is 3.48 and the net production of the system is 4,641 t/km2/year. The matrix of mixed trophic impacts shows that the groups that suffer the greatest negative impact from Sharks are Odontocetes, Mysticetes and Turtles. Changes in the relative biomass of GF were simulated under scenarios of increase and decrease in fishing effort (5 and 10%) and no fishing, over a period of 10 years. It was found that changes in the fishing effort of Elasmobranchs and Finfish have the greatest effect on other GFs. It highlights that suspending fishing would have little effect, both positive and negative (2-3%) on the relative biomass of GFs, except for sharks and rays, which would increase 245 and 124%, respectively. This model could be used for decision making in the management and conservation of the ecosystem.
Ecopath con Ecosim, socio-ecosistema, Golfo de California, pesquerías, conservación Ecopath with Ecosim, socio-ecosystem, Gulf of California, fisheries, conservation BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA OTRAS ESPECIALIDADES DE LA BIOLOGÍA OTRAS OTRAS
Alondra Vargas Barona (2024, [Tesis de maestría])
La enfermedad de Alzheimer (EA) es una enfermedad neurodegenerativa progresiva caracterizada por el deterioro cognitivo asociado a la acumulación de la proteína beta amiloide (Aβ). La Aβ activa a las células gliales del cerebro, generando un aumento en la secreción de citocinas pro-inflamatorias que conducen a la neuroinflamación y muerte neuronal. Actualmente no existen tratamientos efectivos que curen o detengan su progresión, por ello, la EA se considera como una prioridad de salud mundial. Las principales limitaciones son la baja biodisponibilidad del fármaco y la impermeabilidad de la barrera hematoencefálica (BHE). Afortunadamente, la nanomedicina ha surgido como un campo prometedor para el desarrollo de nuevos sistemas para la entrega controlada y dirigida de fármacos hacia el cerebro. Por ello, en este trabajo se sintetizaron nanopartículas híbridas de polímeros y lípidos (NPsHPL) conjugadas con transferrina (Tf) para facilitar el cruce de la BHE, y cargadas con N-acetilcisteína (NAC) por su efecto anti-inflamatorio, y se llevó a cabo su caracterización fisicoquímica. Posteriormente se implementó un modelo in vitro con astrocitos humanos derivados de células pluripotentes inducidas (iPSC) provenientes de un paciente diagnosticado con la EA, las cuales se llevaron a un estado reactivo por la estimulación con lipopolisacárido (LPS). El cultivo de células fue tratado con las NPsHPL conjugadas con Tf y cargadas con NAC (NPsHPL-Tf-NAC) a 0.25 mg/mL y NAC libre a 5 mM. Los resultados mostraron que las NPsHPL-Tf-NAC modularon favorablemente la expresión de genes pro-inflamatorios, como la interleucina-1β (IL-1β), la proteína precursora de amiloide (APP) y la proteína ácida fibrilar glial (GFAP). Además, redujo la secreción de las citocinas pro-inflamatorias interleucina 6 (IL-6), IL-1β e interferóngamma (INF-γ), ambos casos respecto al grupo de células que no recibieron algún tratamiento. Por otra parte, la NAC libre sólo tuvo este efecto en la expresión de IL-1β y la secreción de las citocinas IL-6 e INF-γ. Estos resultados posicionan a las NPsHPL-Tf-NAC como un potencial tratamiento para la EA.
Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by cognitive impairment associated with the accumulation of beta-amyloid protein (Aβ). Aβ activates glial cells in the brain, increasing the secretion of pro-inflammatory cytokines that lead to neuroinflammation and neuronal death. Currently, there are no effective treatments that cure or stop its progression, therefore AD is considered a global health priority. The main limitations are the low drug bioavailability and impermeability of the blood-brain barrier (BBB). Fortunately, nanomedicine has emerged as a promising field for the development of new nanosystems for the controlled and targeted delivery of drugs to the brain. Therefore, in this work, lipid–polymer hybrid nanoparticles (LPHNPs) conjugated with transferrin (Tf) to facilitate crossing the BBB, and loaded with N-acetylcysteine (NAC) for its anti-inflammatory effect were synthesized, and their physicochemical characterization was carried out. Subsequently, an in vitro model with human astrocytes derived from induced pluripotent stem cells (iPSC) from an AD diagnosed patient was implemented, which were brought to a reactive state by stimulation with lipopolysaccharide (LPS). The cell culture was treated with Tf-conjugated LPHNPs loaded with NAC (LPHNPs-Tf-NAC) at 0.25 mg/mL and free NAC at 5 mM. The results showed that LPHNPs-Tf-NAC favorably modulated the expression of pro-inflammatory genes, such as interleukin-1β (IL-1β), amyloid precursor protein (APP) and glial fibrillary acidic protein (GFAP). In addition, they reduced the secretion of the pro-inflammatory cytokines interleukin 6 (IL-6), IL-1β and interferon-gamma (INF-γ), both cases compared to the group of cells that did not receive any treatment. On the other hand, free NAC only had this effect on the expression of IL-1β and the secretion of the cytokines IL-6 and INF-γ. These results position LPHNPs-Tf-NAC as a potential treatment for AD.
nanopartículas híbridas; enfermedad de Alzheimer; neuroinflamación; astrocitos; iPSC; nanomedicina hybrid nanoparticles, Alzheimer’s disease, neuroinflammation; astrocytes; iPSC; nanomedicine BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA OTRAS ESPECIALIDADES DE LA BIOLOGÍA OTRAS OTRAS
NOEMI JARDON MAXIMINO MARIAMNE DEHONOR GOMEZ Rolando Villa Moreno MARIA DOLORES BAEZA ALVARADO Luis Edmundo Lugo Uribe (2023, [Artículo])
Reinforced polymeric composites with natural fibers have garnered significant interest in recent years due to the need for biomass utilization and the requirements of various industries, such as automotive and construction. Among these natural fibers, Agave lechuguilla fiber, commonly known as ixtle (FIx) or Tampico fiber, exhibits important characteristics such as length, high strength, and durability. However, there is limited literature on its conditioning, functionalization, and utilization as a reinforcing material in polymeric composites (CP). This study presents the optimization of the alkali-silane treatment of FIx, identifying the most suitable reaction conditions to enhance their thermal stability, tensile strength, and silane coupling agent (ACSi) grafting on the fiber surface. The chemical treatment with ACSi proved highly effective, resulting in a significant grafting content, which was confirmed through FTIR and SEM–EDS analyses. The high level of functionalization did not compromise the mechanical performance of the fibers, suggesting that functionalized FIx holds great potential as a reinforcing material in CP. These findings open new paths for the sustainable use of Agave lechuguilla fibers, contributing to the development of environmentally friendly and high-performance polymeric composites in various industrial applications.
This article belongs to the Special Issue Natural Fibers for Advanced Materials: Addressing Challenges).
Supplementary materials: The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/fib11100086/s1, Figure S1: Optical microscope image of ixtle fibers at a magnification of 50 (a) untreated and (b) alkaline treated (FIx-5); Table S1: FTIR signal assignment for alkaline treated FIx; Table S2: FTIR Signal assignment for silane treated FIx.
Author contributions: Conceptualization, N.J.-M. and L.E.L.U.; methodology, N.J.-M., M.D.G., R.V.M., M.D.B.-A. and L.E.L.U.; validation, N.J.-M. and L.E.L.U.; formal analysis, N.J.-M., M.D.G. and L.E.L.U.; investigation, N.J.-M. and L.E.L.U.; data curation, N.J.-M., M.D.G., R.V.M. and M.D.B.-A.; writing—original draft preparation, N.J.-M. and L.E.L.U.; writing—review and editing, N.J.-M., M.D.G., R.V.M., M.D.B.-A. and L.E.L.U.; visualization, N.J.-M., M.D.G. and L.E.L.U.; supervision, L.E.L.U.; project administration, N.J.-M. and L.E.L.U.; funding acquisition, N.J.-M. and L.E.L.U. All authors have read and agreed to the published version of the manuscript.
Funding: This research was funded by CONAHCYT, “Estancias postdoctorales por México”, grant umber CVU425480.
Data availability statement: Data supporting the findings of this study are available within the article and upon request from the corresponding author.
Acknowledgments: The authors express their gratitude towards Rene Diaz Rebollar and Jazmin Gomez Sara for their technical assistance in conducting the chemical reactions presented in this current study. Additionally, the assistance provided by Luis Alberto Caceres Diaz in the execution of XRD analyses is also acknowledged. Furthermore, N.J.M. extends sincere recognition to CIATEQ A.C. for their provision of essential resources and infrastructure crucial to the advancement of this research. The support rendered by CONAHCYT through the “Estancias postdoctorales por México” program is also gratefully acknowledged, as it has contributed financial backing to the project. Conflicts of Interest: The authors declare no conflict of interest.
Agave lechuguilla Natural fiber Silane coupling agent INGENIERÍA Y TECNOLOGÍA CIENCIAS TECNOLÓGICAS OTRAS ESPECIALIDADES TECNOLÓGICAS OTRAS OTRAS
Innovative experimental plant to improve coffee processing
IVAN TOVAR ESTRADA Juan Francisco Cedano Lezcano EMANUEL VARGUEZ CALCANEO ESTEBAN GUZMAN RODRIGUEZ (2023, [Artículo])
In Mexico, coffee production refers to a process with traditional processing practices that combine rustic and semi-mechanized activities, where quality is not controlled, placing it in the category of conventional coffee. In recent years worldwide, the demand for high-quality coffee has increased and in order to offer this model, it is necessary to standardize the processing and transformation processes that increase the quality and value of the coffee. In order to exploit the different capacities in our country, it is necessary to design an innovative experimental plant for the processing of the primary coffee beneficiary, which is capable of adapting to the processes known by the producers, through the instruments and machinery the plant will provide The producer has control over the variables that influence taking advantage of the organoleptic properties of the coffee bean prior to harvest. The plant allows experimentation and obtaining controlled results according to the primary processing method to be applied. The development of the experimental plant has three iterative design cycles; 1) concept design, in which the various processes and methods investigated are evaluated to seek their homogenization with the help of instruments for monitoring and control, 2) prototype design, which is carried out with the help of 2D platforms and 3D modeling, that allow visualizing the location of the different equipment, as well as the flows of the different primary processing processes that the producer wishes to apply, and 3) innovation design, in which the products and services allow the value chain to be improved through processes instruments, data control and new techniques. For the development and maintenance of the experimental plant, it is necessary to link the entities that make up the quadruple helix; companies, government, society and public centers and institutes of higher education. In order to promote teamwork, collaboration and the exchange of ideas to strengthen, sustain and enrich the innovation ecosystem created through the experimental plant.
Benefited Specialty coffees INGENIERÍA Y TECNOLOGÍA CIENCIAS TECNOLÓGICAS OTRAS ESPECIALIDADES TECNOLÓGICAS OTRAS OTRAS
Las morales de resistencia indígena en Xochistlahuaca, México.
JOHN KENNY ACUÑA VILLAVICENCIO (2022, [Capítulo de libro])
Las comunidades indígenas del estado de Guerrero, México, han sido las más afectadas por la crisis sanitaria. De manera particular, me refiero a los amuzgos o ñomndaa de la Costa Chica quienes, más allá de cuestionar el débil papel del Estado en controlar la pandemia por coronavirus, han fortalecido su identidad con la naturaleza, puesto que la consideran como parte de su quehacer humano y colectivo. Lo dicho, nos hace entender que esta enfermedad global es resultado de la transformación acelerada que está sufriendo la naturaleza y esto hace que surjan nuevas enfermedades como la COVID-19, además de que se aniquilen creencias, memorias y costumbres.
CIENCIAS SOCIALES CIENCIA POLÍTICA SOCIOLOGÍA POLÍTICA OTRAS
Límites y alcances de la medicina tradicional. Los Amuzgos de Guerrero y la Covid-19.
JOHN KENNY ACUÑA VILLAVICENCIO (2022, [Capítulo de libro])
La cosmovisión de los amuzgos busca sobrevivir en un mundo que avasalla y permea su cultura con costumbres y otras formas alternativas de aliviar y curar enfermedades a través de la medicina tradicional. La visión del amuzgo respecto a las enfermedades es completamente diferente a la que se conoce en el mundo occidental, por lo que es importante visibilizar las prácticas y métodos que utilizan para comprender y retomar este conocimiento que permita generar conexiones e intercambios culturales entre dos saberes distintos: la medicina tradicional y la medicina alópata.
CIENCIAS SOCIALES CIENCIA POLÍTICA SOCIOLOGÍA POLÍTICA OTRAS
JOHN KENNY ACUÑA VILLAVICENCIO (2022, [Capítulo de libro])
En la actualidad, varios han sido los intentos de los líderes políticos y de la salud en lograr que las comunidades amuzgas de la Costa Chica de Guerrero acudan a los hospitales y Centros de Salud para hacerse tratar de algún malestar como los generados por el coronavirus (COVID-19 en sus siglas biológico-químicas), porque se trata de una enfermedad letal en el peor de los casos, sin embargo, el rechazo de los amuzgos es mayor de lo que parece. Estos intentos fallidos tienen que ver con la negación de los indígenas a las formas de atención y tratamiento médico que se le ha brindado al cuerpo, es decir, la mirada positiva y el análisis clínico de la anatomía humana y no de su estado espiritual o catártico en tiempos de crisis o pandemia ha dado lugar a su cuestionamiento. Esta distancia entre la ciencia occidental y tradicional guarda relación con la ausencia de un diálogo que permita establecer la formación de un mundo del reconocimiento y del saber Otro en cuyo eje se articula la salud comunitaria.
CIENCIAS SOCIALES CIENCIA POLÍTICA SOCIOLOGÍA POLÍTICA OTRAS
Luis Ricardo Uribe Dávila (2023, [Tesis de maestría])
Vivimos la industria 4.0, misma que no es nueva, ya que sus orígenes se remontan a finales de la década de los 2000, en Alemania. Un pilar de la industria 4.0 es el análisis de datos, conocido como Big Data. El conocer los datos de un proceso, de un estudio, ayuda en gran medida a predecir el comportamiento que tendrá el proceso o la máquina a estudiar en un periodo a corto o mediano plazo. En el presente proyecto se analizan los datos arrojados por un motor eléctrico de corriente alterna, del tipo inducción, jaula de ardilla. El motor está diseñado para trabajar de manera continua, sin embargo, el uso que se le da, es meramente educativo; es decir, no sobre pasa las 15 horas por semana de uso. Mediante la toma de datos de las tres fases de corriente RMS o corriente de valor eficaz que posee el motor eléctrico que se realizará con el microcontrolador Arduino UNO, se analizarán los mismos mediante el software de cómputo numérico MATLAB, ordenando los datos, descartando valores que no aporten información relevante para lograr la predicción de datos. Por último, se llevará a conocer este proyecto a la carrera mecatrónica, área sistemas de manufactura flexible y área automatización, con el fin de que puedan observar de una mejor manera la aplicación y funcionamiento de uno de los pilares de la actual industria 4.0.
We live in industry 4.0, which is not new, since its origins date back to the late 2000s, in Germany. One pillar of industry 4.0 is data analysis, known as Big Data. Knowing the data of a process, of a study, helps greatly to predict the behavior that the process or machine will have to study in a short- or medium-term period. This project analyzes the data released by an electric motor of alternating current, of the type induction, squirrel cage. The engine is designed to work continuously, however, the use given to it is merely educational, that is; only not over spends 15 hours per week of use. By taking data from the three phases of RMS current or effective value current of the electric motor that will be made with the Arduino UNO micro controller, they will be analyzed using MATLAB numerical computing software, ordering the data, discarding values that do not provide relevant information to achieve data prediction. Finally, this project will be presented to the mechatronics career, flexible manufacturing systems area and automation area, so that they can observe in a better way the application and operation of one of the pillars of the current industry 4.0.
Mantenimiento predictivo Regresión lineal Industria 4.0 Big data Corriente RMS Predictive maintenance Linear regression Industry 4.0 Big data RMS Current INGENIERÍA Y TECNOLOGÍA CIENCIAS TECNOLÓGICAS OTRAS ESPECIALIDADES TECNOLÓGICAS OTRAS OTRAS
In-service weld repair by direct deposition: numerical simulation and experimental validation
LUIS DANTE MELENDEZ MORALES Jose Jorge Ruiz Mondragon MARICRUZ HERNANDEZ HERNANDEZ (2023, [Artículo])
In-Service Welding is a technological process for which interconnection and repair of pipelines can be made while they are in operation, before making it two main risks need to be assessed: hydrogen cracking and burn-through. Current simulations and validations assess these risks independently, but due to its interdependence these risks need to be assessed in conjunction. A repair method not normally used, but with high potential due to its simplicity and versatility is the direct deposition of weld. In the present research, a fluid-thermo-mechanical coupled simulation and validation were done of an in-service welding repair by direct deposition on a flowing pressurized pipe having an internal defect. The results demonstrated the effectiveness of using this repair method to restore the mechanical strength of pipelines. Surface, sub-surface, and volumetric non-destructive examinations evidenced no cracking immediately to finish the repair and delayed. Temperature tendency curves showed good approximations having a maximum difference of 5.09 % between numerical and experimental. Perimeter deformation along the pipe length between numerical and experimental results displayed a similar behaviour with a significant difference in the numerical values attributed to the lack of input data for weld properties. The structural analysis performed in this study used the approach of the risk of burn-through under internal pressure determined by the occurrence of localized radial bulging. Numerical results indicated no relevant plastic strain occurs. Is strongly recommended that thermal analysis assessments using the actual defect morphology would be performed, not only considering the remaining thickness of the pipe.
Declaration of Competing Interest: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Acknowledgements: The authors gratefully acknowledge to Petropipe de Mexico for technical support, materials and equipment needed for the experimental validation. The first author wants also to acknowledge to CONAHCYT (Consejo Nacional de Humanidades, Ciencias y Tecnologías), for the post-graduate scholarship received.
In-service welding Burn-through Hydrogen cracking Weld repair INGENIERÍA Y TECNOLOGÍA CIENCIAS TECNOLÓGICAS OTRAS ESPECIALIDADES TECNOLÓGICAS OTRAS OTRAS
Aaron Azael Lopez Cano VERONICA MARTINEZ AGUILAR Mariana Peña-Juárez Ricardo López Esparza Enrique Delgado Alvarado Emmanuel Gutierrez MAYRA DEL ANGEL MONROY Elias Perez Agustin L. Herrera-May JOSE AMIR GONZALEZ CALDERON (2023, [Artículo])
We explored the potential of different nanoparticles (TiO2, CaCO3, and Al2O3), considering their pure form and modified with cinnamon essential oil (CEO). These materials were characterized using various techniques, including FTIR spectroscopy, XRD analysis, TGA, and SEM. The interaction between CEO and nanoparticles changed depending on the nanoparticle type. Al2O3 nanoparticles exhibited the strongest interaction with CEO, increasing their antioxidant capacity by around 40% and their transfer of antimicrobial properties, particularly against Gram-negative bacteria. In contrast, TiO2 and CaCO3 nanoparticles showed limited interaction with CEO, resulting in lower antioxidant capacity and antimicrobial activity. Incorporating pure and CEO-modified nanoparticles into polylactic acid (PLA) films improved their mechanical and thermal properties, which are suitable for applications requiring greater strength. This research highlights the potential of metal oxide nanoparticles to enhance the antimicrobial and antioxidant capabilities of polymers. In addition, incorporating cinnamon essential oil can increase the antioxidant and antimicrobial effectiveness of the metal oxide nanoparticles and improve the mechanical and thermal properties of PLA films. Thus, these PLA films exhibit favorable characteristics for active packaging applications.
Author contributions: conceptualization, V.M.-A. and J.A.G.-C.; formal analysis, A.A.L.-C., V.M.-A., M.G.P.-J. and M.D.A.-M.; funding acquisition, A.L.H.-M.; methodology, A.A.L.-C. and V.M.-A.; investigation, E.P.; supervision, R.L.-E., E.D.-A., and E.J.G.-C.; validation, A.L.H.-M. and J.A.G.-C.; writing—original draft, V.M.-A.; writing—review and editing, M.G.P.-J. and J.A.G.-C. All authors have read and agreed to the published version of the manuscript.
Funding: J.A. Gonzalez-Calderon thanks CONAHCYT for supporting the Catedras-CONAHCYT Program, and Verónica Martinez thanks CONAHCYT for the Doctoral Fellowship. The authors also want to thank CONAHCYT for funding the project CF2019 265239 “Ciencia de Frontera”, which made this work possible.
Institutional review board statement: Not applicable.
Informed consent statement: Not applicable.
Data availability statement: Data is contained within the article.
Acknowledgments: The authors acknowledge Claudia Hernández and Rosa Lina Tovar for their support during the XRD and SEM analyses.
Conflicts of interest: The authors declare no conflict of interest.
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Cinnamon essential oil Antioxidant activity Antimicrobial properties Nanoparticles Polylactic acid films INGENIERÍA Y TECNOLOGÍA CIENCIAS TECNOLÓGICAS OTRAS ESPECIALIDADES TECNOLÓGICAS OTRAS OTRAS