DEPRESSIVE SYMPTOMS (DS) AND CITIES: A SOCIOECONOMIC PERSPECTIVE FOR THE MEXICAN CASE

Jorge López Martínez Déborah Féber González (2023, [Artículo, Artículo])

This article presents an analysis of the proportion of the population that lives in the 20 top cities of Mexico. Population that suffers from moderate to severe Depressive Symptoms (DS) in relation to urban and socioeconomic factors typical of urban territories and comparing them with people living in rural or non-urban environments that suffers DS. To check this, we generated the Complex Index of Socioeconomic and Urban Conditions (CISUC), based on the Mind the GAPS framework, a model that relates the susceptibility or prevention of mental illness in cities based on urban factors, we also used socioeconomic indicators that exist in Mexican cities. For the construction of the ICCSU database, we used data from the National Health and Nutrition Survey in the years 2006, 2012 and 2018-19 and the data of the Mexican Institute for Competitiveness, A.C. and National Institute of Statistics and Geography in the same years. The results obtained from CISUC were reinforced with the use of a panel data model. The findings that we obtained reveal that there is a more important correlation between cities and people who suffer from moderate to severe DS than in rural areas, a condition that intensifies with the socioeconomic conditions of the population, for example, their socioeconomic stratum, their gender, and present urban marginalization. This allows to generate future discussions about other types of diseases such as anxiety, depression, stress, loneliness, and schizophrenia for large population groups. The panel model yields a lower goodness of adjustment, due to the lack of more time points, however, it points out that improvements in socioeconomic and urban conditions slightly reduce depressive symptoms.

mental health depressive symptoms (DS) urban marginalization socioeconomic factors cities salud mental sintomatología depresiva (SD) ciudades marginación urbana factores socioeconómicos CIENCIAS SOCIALESCIENCIAS SOCIALES CIENCIAS SOCIALES

Gene expression in primary hemocyte culture of the Pacific white shrimp Penaeus vannamei infected with different white spot syndrome virus (WSSV) strains

Delia Patricia Parrilla Taylor REGINA ELIZONDO GONZALEZ Jesús Neftalí Gutiérrez Rivera SILVIA ALEJANDRA GARCIA GASCA NORBERTO VIBANCO PEREZ MA. DE JESUS DURAN AVELAR RICARDO VAZQUEZ JUAREZ (2022, [Artículo])

"Five previously analyzed white spot syndrome virus (WSSV) strains from northwest Mexico,differing in their genome architecture as well as in virulence, were selected (high virulence JP and LG strains;moderate virulence GVE and DIV strains; and low virulence LC10 strain) to evaluate pathogenesis response in vitro. Expression of phagocytosis-activating protein PAP, manganese superoxide dismutase MnSOD and peroxiredoxin PRX, and two genes of immediate-early expression (IE1 and WSSV304) were measured by qPCR in a primary hemocyte cell culture from Penaeus vannamei at 1, 3, 6, 12, and 24 h post-infection (hpi). PAP expression was significantly higher at 1 and 3 hpi, and JP and LC10 strains induced the highest expression. The response of MnSOD was high at 1 hpi, and a significant increase in PRX expression was detected at 3 hpi, probably due to the occurrence of an oxidative burst; expression levels of MnSOD and PRX were significantly higher at 1 and 3 hpi, respectively, induced by the LG strain (high virulence), suggesting an acute response. In general, expression of most immune-related - genes decreased after the initial hours of infection. Expression levels of IE1 and WSSV304 were exceptionally high at 1 hpi in almost all five WSSV analyzed strains,confirming their efficient mechanism for replication and viral fitness. The results of this study do not show an accurate link between the genome size and WSSV virulence of the strains, albeit the strain with the smallest genome showed the highest virulence. All strains induced an early immune response in heterogeneous ways."

Penaeus vannamei, virulence, gene expression, viral fitness, viral pathogenesis, immune response BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA BIOLOGÍA ANIMAL (ZOOLOGÍA) PATOLOGÍA ANIMAL PATOLOGÍA ANIMAL